More than a million people in the UK have type 2 diabetes and the number is rising sharply. Genes play an important role in the development of diabetes, although the mechanisms for this are not well understood. The Norfolk Diabetes Case Control Study will help to identify genetic factors linked to type 2 diabetes and its complications. The study aims to contribute to a better understanding of how diabetes develops and how it can be prevented and treated better.
This is a case-control study of type 2 diabetes which recruited 6974 prevalent cases of Type 2 diabetes from practices in Norfolk, with cases then matched to EPIC controls. This provided a population-based case-control study which contributes to our understanding of the genetics of type 2 diabetes.
Field work completed with on-going use of genetic data for meta-analysis.
Unit responsible for data and samples and continuing analysis.
This work was funded by the Medical Research Council (MRC) and the Wellcome Trust in collaboration with the Norfolk and Norwich University Hospitals NHS Foundation Trust in Norfolk. Continued preservation and use is funded by Unit core MRC grant.