It is common for people to develop cardiovascular disease, obesity, diabetes, raised cholesterol and high blood pressure after a liver transplant. This increases the risk of poor health and lowers quality of life. A healthy diet and physical activity are important to enable people to stay healthy after transplant. We don’t know whether people have a healthy diet and are physically active after a transplant or not, or what influences these behaviours. This may be different to the general public due to the effects of liver disease, the transplant operation and medication.
The BOLT (behaviours and outcomes after liver transplant) study aims to find out, for liver transplant recipients:
- What are their diet and physical activity behaviours?
- What are the factors influencing these behaviours?
- Are diet and physical activity behaviours associated with cardiovascular disease risk factors and quality of life?
Knowing the answers to these questions will help to improve post-transplant care.
What will this research involve?
We will invite patients who have had a liver transplant at Cambridge University Hospitals NHS Foundation Trust and are between 6 months and three years post-transplant to take part. We will measure quality of life, diet, physical activity and things that might influence diet and activity. We will collect information on risk factors for cardiovascular disease, such as blood pressure and cholesterol levels. With this information we will look at the links between diet, activity, cardiovascular disease risk factors, quality of life and the reasons for diet and activity behaviours
We will invite some participants from part 1 of the study to interviews to explore the things influencing their diet and activity in more depth. We will choose people who have a range of diet and activity behaviours, so that a range of experiences are explored.