Heritability of overall activity level has been estimated to be around 40% from twin studies and about 20% from genetic studies; however heritability for the underlying patterns of accumulation has not been examined. This project will use classic twin study designs as well as genome-wide association studies (GWAS) to investigate the heritability of activity accumulation patterns.
Heritability of objectively assessed daily physical activity and sedentary behavior. den Hoed M, Brage S, Zhao JH, Westgate K, Nessa A, Ekelund U, Spector TD, Wareham NJ, Loos RJ. Am J Clin Nutr. 2013;98(5):1317-25.