Visiting Clinical Fellow
Aetiology of Diabetes and Related Metabolic Disorders, Metabolic Research Laboratories, and Department of Paediatrics
Current work and interests
Jake is a clinical paediatrics registrar and his research interest is in liver fat (hepatic steatosis). He is particularly interested in genetic influences that lead to development of steatosis and the non-alcoholic fatty liver disease (NAFLD) spectrum. He works between the MRC Epidemiology Unit, Metabolic Research Laboratories, and the Department of Paediatrics.
His current research in the Unit, supervised by Dr Claudia Langenberg and Professor Nick Wareham in the Aetiology of Diabetes and Related Metabolic Disorders programme, has two main aspects:
- Assess the relationships between body fat distribution, insulin resistance, and liver fat, and how this is influenced by common genetic variants
- Searching for blood tests (‘serum biomarkers’) that might be useful for predicting who may progress to more advanced liver disease