Senior Investigator Scientist
Jing Hua Zhao was an investigator scientist at the Unit with research interests in statistical and computational genetics. He received a bachelor’s degree in public health from Shandong Medical University, China and a master’s degree in medical statistics from Shanghai (Fudan) Medical University, China. He then came to the UK as a researcher in genetics at King’s College London where he was awarded a PhD in genetics. He left the Unit in May 2018.
His past positions include:
- Research Associate at Centre for Health Statistics Information, Ministry of Health, China
- visiting Scientist at the Department of Environmental Health, School of Public Health, and the Channing Laboratory, Harvard University
- Research Associate at the Institute of Psychiatry, King’s College London
- Statistician at the Department of Epidemiology and Public Health, University College London.
Jing Hua Zhao has worked on design and analysis for Whitehall II, ELSA, EPIC-Norfolk, InterAct and the Framingham Heart Study via genetic analysis workshops. The EPIC-Norfolk gonomewide association study contributed to consortia such as GIANT and CHARGE. He is a member of the Royal Statistical Society.
He promotes reproducible research, in particular genetic data analysis with R, through software development, presentations and/or tutorials at useR!2007, useR!2008, useR!2009, useR!2010, useR!2011, Henry-Stewart talks and and other local talks. He also distributes software, for example the genetics analysis package (gap) on CRAN.
Selected publications
- Xue F. Li S. Luan J. Yuan Z. Luben RN. Khaw KT. Wareham NJ. Loos RJ. Zhao JH. A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study. PLoS One. 2012;7(2):e31927. doi: 10.1371/journal.pone.0031927
- Zhao JH. and Luan J. Mixed Modeling with Whole Genome Data. Journal of Probability and Statistics, Volume 2012 (2012), Article ID 485174, 16 pages. doi: 10.1155/2012/485174
- Zhao JH. Gap: genetic analysis package. J Stat Soft 2007;23(8):1-18 Open access publication
- Zhao JH, JA Luan, F Baksh, Q Tan. Mining gene networks with application to GAW15 problem 1. BMC Proceedings 2007;1(Suppl 1):S52
- Tan Q, Christiansen L, Brasch-Andersen C, Zhao JH, Kruse TA, Christensen K. Retrospective analysis of main and interaction effects in genetic association studies of human complex traits. BMC Genetics 2007;8:70
- Zhao JH, JA Luan, Q Tan, R Loos, N Wareham. Analysis of Large Genomic Data in Silico: The EPIC-Norfolk Study of Obesity. In DS Huang, L Heutte, and M Loog (Eds). ICIC2007, CCIS 2 Advanced Intelligent Computing Theories and Applications with Aspects of Contemporary Intelligent Computing Technologies 781-790.
- Zhao JH, Q Tan. Genetic dissection of complex traits in silico: approaches, problems and solutions. Curr Bioinformatics 2006;1(3):359-369
- Zhao JH, Q Tan. Integrated analysis of genetic data with R. Hum Genomics 2006;2(4):258-265
- Tan Q, K Christensen, L Christiansen, L Bathum, S Li, JH Zhao, TK Kruse. Haplotype association analysis of human disease traits using multi-locus genotype data of unrelated subjects. Genetical Res 2005;86:223-231
- Zhao JH. Mixed-effects Cox models of alcohol dependence in extended families. BMC Genetics 2005;6(Suppl 1):S127
- Zhao JH, EJ Brunner, M Kumari, A Singh-Manoux, E Hawe, PJ Talmud, MG Marmot, SE Humphries. Longitudinal study of APOE polymorphism, socioeconomic status and cognitive function in later mid-life: the Whitehall II study. Soc Psychiatr and Psychiatr Epidemiol 2005;40:557-563