MRC Epidemiology UnitSenior Epidemiology Studies Manager (Cambridge Epidemiology & Trials Unit)
Study Coordination, Field Epidemiology
Current work and interests
Sylvaine Bruggraber joined the Unit in May 2022 as Senior Epidemiology Studies Manager for the Cambridge Epidemiology and Trials unit (CETU) and is responsible for the Study Coordinator and the Field Epidemiology teams.
Background and experience
Sylvaine obtained her PhD in Bioinorganic Chemistry at King’s College London where she designed low molecular weight metal-ion complexes to be specifically active against Helicobacter pylori, the bacterium responsible for most duodenal and gastric ulcers. She then transitioned to a post-doctoral Research Assistant position at UC Davis, California (department of Rheumatology, Allergy and Clinical Immunology) where she developed a method to accurately detect the binding of anti-mitochondrial antibodies from human sera to xenobiotic-transformed peptides.
In 2004, Sylvaine joined the MRC Human Nutrition Research Unit where she invented a novel type of metal ion based material whilst co-investigator and project manager on a project funded by MRC Technology (now LifeArc). In this role she oversaw the post-licensing transfer of a novel phosphate binder to an industrial partner. Following this Sylvaine directed the trace elements analysis lab working on projects within the Unit and with external organisations, including analysis of urinary iodine for the UK National Diet and Nutrition Survey rolling programme.
In 2016, Sylvaine joined the Department of Paediatrics (University of Cambridge) as Senior Study Manager where she lead the clinical work for a large pan European consortium in Type 1 Diabetes and contributed to the development of a Master Protocol for adaptive studies in new onset type 1 diabetes and its adaptation to 4 novel clinical trials run within the INNODIA consortium.