Aetiology and Mechanisms of Diabetes and Related Metabolic Disorders of Later Life

Left the Unit in 2022

Work and interests

Eleanor was a Senior Research Associate whose research focuses on using large-scale data sets including SNP array data and publicly available resources to identify genes of interest and to help understand the mechanisms underlying diabetes, obesity and related quantitative traits.

Following completion of her PhD in statistical Genetics at the University of Cambridge, Eleanor worked at the Wellcome Sanger Institute before joining the Unit in 2018.

Publications

• MRC Epidemiology Unit publications on Publications Database

Selected publications

1. Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. PLoS Med. (2017), 14(9):e1002383. doi:10.1371/journal.pmed.1002383.  PMID: 28898252.
2. Wheeler E, Huang N, Bochukova EG, Keogh JM, Lindsay S, et al. Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. Nat Genet. (2013), 45(5):513-7. doi: 10.1038/ng.2607. PMID: 23563609.