Common genetic factors that influence muscle strength in humans have been identified for the first time in a study led by researchers from the University of Cambridge and published today […]
Generation Genome – providing the knowledge for disease prevention and treatment.
Yesterday Professor Sally Davies, the Chief Medical Officer (CMO) for England, published Generation Genome, the Chief Medical Officer’s annual report for 2016. In her report she takes a detailed look […]
Genetic differences in amino acid metabolism are linked to a higher risk of type 2 diabetes
A study published today in the journal PLOS Medicine has identified the five genetic variants associated with higher levels of the branched-chain amino acids isoleucine, leucine and valine. The researchers […]
Inability to safely store fat increases risk of diabetes and heart disease
A large-scale genetic study has provided strong evidence that the development of insulin resistance – a risk factor for type 2 diabetes and heart attacks and one of the key […]
New genetic analysis provides insight into side effects of cholesterol lowering drugs
A new meta-analysis of genetic association studies, published today in the Journal of the American Medical Association (JAMA), is shedding light on the mechanisms through which LDL-cholesterol lowering drugs can […]
Genetic approach could help identify side-effects at early stages of drug development
An approach that could reduce the chances of drugs failing during the later stages of clinical trials has been demonstrated by a collaboration between the University of Cambridge and pharmaceutical […]
The future of diabetes prevention: submissions open for PLoS Medicine special issue
As 2015 came to a close Professor Nick Wareham, Director of the MRC Epidemiology Unit, joined an multidisciplinary panel of experts in a PLoS Medicine editorial that took stock of […]
Analysis of data from 140,000 individuals cast doubts on clinical value of current definitions of metabolic health
Definitions of metabolic health that have been proposed to help explain differences in the risk of developing type 2 diabetes between people of different weight may be less helpful than […]
Early detection and treatment of type 2 diabetes may reduce heart disease and mortality
Screening to identify type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research published today in Diabetes Care that combined large scale clinical […]
Universal approach to tackling unhealthy lifestyles more appropriate for combating diabetes than focusing on genetic risk
Public health strategies aimed at tackling obesity at a population level through lifestyle changes are more appropriate for preventing type 2 diabetes than targeted interventions based on an individual’s genetic […]