In a study undertaken in more than 10,000 individuals, and published today in Nature Communications, scientists have shown that integrating information derived from different technologies to measure proteins can identify […]
How our brain uses nutritional state to regulate growth and age at puberty
Scientists have discovered how a receptor in the brain, called MC3R, detects the nutritional state of the body and regulates the timing of puberty and rate of growth in children […]
Filling the gaps: connecting genes to diseases through proteins
Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by Unit scientists, challenging the categorisation of […]
Young adults at highest risk of weight gain
Young adults aged 18 to 24 are at the highest risk of becoming overweight or developing obesity in the next decade of their life compared to adults in any other […]
Rare genetic variants confer largest increase in type 2 diabetes risk seen to date
Scientists at the University of Cambridge have identified rare genetic variants – carried by one in 3,000 people – that have a larger impact on the risk of developing type […]
Ethnic diversity in research identifies more genomic regions linked to diabetes-related traits
By including multi-ethnic participants, a largescale genetic study has identified more regions of the genome linked to type 2 diabetes-related traits than if the research had been conducted in Europeans […]
New study finds shared origins for individual chronic diseases in multimorbidity
A new study published today in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing not only one but multiple non-communicable diseases, which include cardiovascular disease, […]
Discovery of genetic regulators of human metabolism and health
An international team led by researchers at the MRC Epidemiology Unit has used a cross-platform approach across several large human studies to identify hundreds of novel genetic variants that regulate […]
Consortium led by Unit researchers develops open platform to help discover COVID-19 drugs
An international consortium led by MRC researchers has developed an open access platform to help prioritise drug discovery and repurposing efforts for the current COVID-19 pandemic. The platform provides information on […]
Unit scientists join call for urgent action to address global diabetes epidemic
Researchers from the MRC Epidemiology Unit are part of the international team behind a new report in The Lancet summarising the best evidence for effectively managing and preventing diabetes. This […]