Type 2 diabetes is typically characterised as a progressive irreversible condition. However, there is evidence that people with type 2 diabetes can achieve good glucose control or even remission through weight loss. Most studies that demonstrate this have used bariatric surgery or formula diets, which are rarely commissioned in the UK because of their high cost and reliance on specialists. In the UK, standard care for people with a new diagnosis of type 2 diabetes is structured diabetes education, which has low uptake and small, short term effects on weight and blood glucose.
The GLoW (Glucose Lowering through Weight management) trial will evaluate whether a tailored behavioural weight management programme that can be delivered at scale achieves better glucose control and other health outcomes than education alone. It will also evaluate whether any improvements in health and wellbeing justify the higher cost of the programme.